Here is the full list of answers to questions we've received during the abm Viral Vectors - How to Design, Run, and Optimize Your Gene Delivery Experiment webinar:
- What is titer?
- How do I decide what virus titer to use? Is there a guideline for in vitro work? In vivo work?
- Can you please tell me what is DNA integration and why does it matter to decide which viral vector to use?
- How safe are the recombinant viruses? If I get them, do I need special facility to handle it?
- Do you have to ship viruses on dry ice or is blue ice ok?
1. What is titer?
Titer refers to the amount of virus in a solution, and it is a way of expressing concentration. For example, if we say a lentivirus has a titer of 1x106 IU/ml, this means that there is 1 million viral particles per millilitre, where IU stands for Infectious Units.