Molecular Minutes

Colon Cancer Biomarkers Guide

Posted by Applied Biological Materials (abm) on March 17, 2020

 

Did you know that colon cancer is more common in developed countries? Around 65% of cases are found in these regions.13 In fact, colorectal cancer is the third most common cancer in the world and is diagnosed in 1 out of every 10 diagnoses.1 As such, it is a major focus in cancer research.

Tumour markers are generally proteins expressed in normal/healthy and cancer cells, but are expressed at an abnormal level in cancer cells.2 Thus, tumour markers serve as a way to diagnose and detect some types of cancers, with immunohistochemistry (IHC) being an important tool for identifying different colon cancers.

In this article, we’ll discuss the gene expression landscape of colon cancer and identify key markers for this disease.

  1. Overexpressed genes
  2. Underexpressed genes
  3. Cell cycle markers
  4. Cell surface markers
  5. Summary of colon cancer markers
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Topics: Biomarkers Guide, Colon Cancer, Histology

Featuring Instagram Science Communicator, Daisy!

Posted by Applied Biological Materials (abm) on February 20, 2020

We recognize that science can seem difficult to young scientists, and we hope to raise awareness about people who make it fun and accessible to broader audiences through social media, #SciComm!

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Meet Daisy, a postdoc who's traveled halfway around the world on a mission to study retinal eye diseases. Daisy uses her Instagram and Twitter accounts to share information about her research, short videos from the lab and updates on her travels. We got the chance to ask Daisy a few questions to learn more about her and her research!


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Topics: #SciComm

Your Basic Guide to Cell Line Immortalization

Posted by Applied Biological Materials (abm) on February 12, 2020

 

You’ve probably heard the saying, “all good things come to an end” - especially when it comes to precious primary cell cultures that reach senescence after a few passages. Thanks to the development of immortalized cell lines, however, this is no longer true! In this blog post we’ll go over:

  1. What are immortalized cells
  2. Strategies for generating immortalized cells
  3. An overview of the immortalization workflow
  4. Cell line quality control considerations
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Topics: Cell Culture, Cell line

Featuring Instagram Science Communicator, Tori Quintana!

Posted by Applied Biological Materials (abm) on February 4, 2020

We recognize science can seem difficult to young scientists, and we hope to raise awareness about people who make it fun and accessible to broader audiences through social media, #SciComm!

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Meet Tori Quintana, a science communicator and PhD student studying Cancer biology. Through her Instagram account @tinybutmightyscientist Tori shares the challenges and accomplishments she experiences both in her professional and personal life, and shares the advice she's learned! We got the chance to ask Tori a few questions about her research, her hobbies and her experience as a women in STEM. 

 


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Topics: #SciComm

We were cited in 3,000+ journals by the end of 2019!

Posted by Applied Biological Materials (abm) on February 1, 2020

We are happy to announce that by the end of December 2019, abm's products have been cited in 3,000+ publications - our citations list is growing at an incredible rate!

View the complete list of publications here, which includes high-impact journals such as Cell, Nature, and Science.

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Topics: Announcement

RNA Mango: Track your RNA in Action!

Posted by Applied Biological Materials (abm) on January 28, 2020
Track your RNA in action with the novel RNA Mango fluorescent imaging system
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Topics: RNA Mango

Featuring Instagram Science Communicator, Jen, 'A Bookish Scientist'!

Posted by Applied Biological Materials (abm) on January 14, 2020

We recognize science can seem difficult to young scientists, and we hope to raise awareness about people who make it fun and accessible to broader audiences through social media, #SciComm!

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Meet Jen, also known as "A Bookish Scientist" on Instagram. She is a first year Cancer Biology PhD student and bookworm, who recommends good books and gives PhD tips to her follower base of almost 10K on Instagram!  


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Topics: #SciComm

What is Multiplicity of Infection (MOI)?

Posted by Applied Biological Materials (abm) on January 1, 2020

So you’ve packaged your DNA into a virus and you’re ready to infect your cells! But, how many viral particles are required for 100% infection? In this blog post and video, we’ll explain the concept of Multiplicity of Infection or MOI and take you through how to determine the best MOI for your experiment.

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Topics: Viral Vectors, Multiplicity of Infection

A New Year, A New Website

Posted by Applied Biological Materials (abm) on December 18, 2019

abm is excited to announce that we will be launching our new website in early 2020!

When abm was first founded in 2004, our goal has always been to make research more accessible. Today, our catalog has grown to over a million products and calls for a new website that can better connect scientists like you with the tools you need for your research.

Take a sneak peek at how we improved our product navigation, customer portal experience, mobile optimization and most importantly, our new rewards program.


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Topics: Announcement

Featuring Instagram Science Communicator, Sophie Arthur!

Posted by Applied Biological Materials (abm) on December 12, 2019

We recognize science can seem difficult to young scientists, and we hope to raise awareness about people who make it fun and accessible to broader audiences through social media, #SciComm!

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Meet Sophie Arthur, an award-winning science & education blogger. She currently works for the MRC London Institute of Medical Sciences as their scicomm officer.

Her job is to share the world leading medical research her colleagues do! She does this through social media by creating content for their website, filming videos, hosting events for schools and the general public and so much more!

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Topics: #SciComm

Molecular Minutes

Sharing the latest breakthroughs in biotech and helpful tips for life scientists working in the lab.

For more in-depth articles, check out our knowledge base, which covers topics such as CRISPR, Next Generation Sequencing, PCR, Cell Culture, and more.

Blog managed by Applied Biological Materials (abm). 

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